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By means of HPLC-ESI-QTOF-MS, the metabolic intermediates of DEHP are identified for SP4, which include mono-2-ethylhexylphthalate (MEHP), mono-butyl phthalate (MBP), phthalic acid (PA), salicylic acid (SA), and 4-oxo-hexanoic acid

Mait establishes realistic timelines based on individual assessment and treatment goals

What the restriction achieved was to keep that use entirely outside the pharmaceutical quality system where they may be no control over what was in the vial or over the concentration or sterility

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But there is also a risk of this treatment: In 2% to 7% of patients treated with tPA within the recommended time window of 4.5 hours hemorrhagic transformation occurs